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Hurthle cell
A Hürthle cell is a cell in the thyroid that is often associated with Hashimoto's thyroiditis〔(【引用サイトリンク】title=Endocrine Pathology )〕 as well as follicular thyroid cancer. Hürthle cell cancer is considered a variant of follicular thyroid cancer. This version is a relatively rare form of differentiated thyroid cancer, accounting for only 3-10% of all differentiated thyroid cancers. Oncocytes in the thyroid are often called Hürthle cells. Although the terms oncocyte, oxyphilic cell, and Hürthle cell are used interchangeably, Hürthle cell is used only to indicate cells of thyroid follicular origin.〔Cannon, J. (2011). The Significance of Hurthle Cells in Thyroid Disease. The Oncologist. doi:10.1634/theoncologist.2010-0253〕
==History==
The Hürthle cell is named after German histologist Karl Hürthle, who investigated thyroid secretory function, particularly in dogs. However, this is a misnomer since Hürthle actually described parafollicular C cells.〔 The cell known as the Hürthle cell was first described in 1898 by Max Askanazy, who noted it in patients with Graves' disease.〔〔M. Askanazy. Pathologisch-anatomische Beiträge zur Kenntniss des morbus basedowii, insbesondere uber die dabei auftretende Muskelerkrankkung. Deutsches Archiv für klinische Medicin, Leipzig, 1898, 61:118-186.〕 James Ewing first coined the term "Hürthle cell" in his 1919 oncology textbook in reference to the cell which Askanazy had first described.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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